Positive Reasons for Stem Cell Storage


Positive Reasons Why to Consider Dental Stem Cell Storage:

                                                                              

  1. The loss of primary teeth happens naturally because they are only temporary, and more importantly, they can be removed with minimal discomfort to the children, during a regular visit to the pediatric dentist. Thus, children’s teeth are an unlimited source of young stem cells with easy access;
  2. Children have multiple storage opportunities, 20 primary teeth in all, giving many opportunities for collection and storage. However, only 12 teeth that can be used for this collection, in fact, not all tooth contains cells with this potential (mainly incisors and canines with at least one third of root left). Thus, unlike umbilical cord blood banking which offers only one chance to collect and save cord tissue stem cells, the window of opportunity in milk teeth stem cell banking is much bigger;
  3. The isolation of stem cells from teeth is simple, non-invasive and painless for your children when compared with derivations from other tissues of the body such as cord blood, peripheral blood and bone marrow;
  4. Cells isolated from primary teeth possess usually better properties than when they are taken from adults since they are less disturbed by elements such as illness and ageing, which can decrease the potentialities of these cells;
  5. Children’s teeth stem cells are adult stem cells and do not require the same ethical concerns as embryonic stem cells. They are autologous stem cells extracted from one's own body and therefore there are no ethical problems involved in their use. Thus, these stem cells can be isolated, manipulated and cryopreserved to later treat children who require stem cells transplants;
  6. Milk teeth stem cells replicate faster and longer than those isolated from other tissues of the body. Thus, you can have an adequate number of cells for transplantation purposes;
  7. Stem cells collected from primary teeth that fall out offer an amazing potential for the future healthcare of our children than cord blood. In fact, unlike cord blood, which must be collected in the minutes after birth, milk tooth stem cells can be isolated practically every time when children’s tooth falls out. Thus, the storage of primary teeth stem cell is an opportunity for parents who have not banked cord blood of their children;
  8. Stem cells present in the human body lose their regenerative capacity during aging whereas children tooth stem cells due to the fact that were collected at the age of 6-8 years old have a high potential for medical applications;
  9. Children’s teeth stem cells share a common origin with neural tissue, thus these cells could one day regenerate brain neurons that die in Parkinson's disease, one of the most common neurological disorders affecting approximately 6.3 million people worldwide;
  10. These cells could be used for autologous transplant (a transplant using the patient’s own stem cells). Thus, they do not induce an immunoreaction or a tissue rejection when transplanted later in life and do not need an immunosuppressive therapy;
  11. Children’s teeth stem cells could be also used for close relative of the donor such as siblings, parents, uncles and grandparents;
  12. If your children, later in life, need to replace some tissue for whatever reason, the stem cells saved from their baby teeth can be utilized to regenerate and repair the needed tissue. Thus, the practice of storing baby teeth could potentially save the life of your children;
  13. While cord blood stem cells are able to generate blood cell types, children’s teeth stem cells have proven valuable in the regeneration of solid tissues such as connective, dental, bone and neural tissues;
  14. Children’s teeth stem cells could be successfully used in the following areas: bone tissue engineering, muscle repair, vascular insufficiencies, tooth reconstruction, periodontitis, skin burns, muscular dystrophy, peripheral nerve repair, corneal reconstruction, diabetes, wound healing, spinal cord injury, myocardial infarction and liver repair (see Figure);
  15. Banking children’s teeth stem cells means that children can take benefit of stem cell therapies in use today but also future therapies not yet approved;
  16. The cost of children’s teeth stem cells storage is 1/3 of the cost of cord blood storage;
  17. The long-term cryopreservation (storage) did not affect the biological properties of children’s tooth stem cells. Therefore, milk teeth are an optimal source for stem cell banking;
  18. If properly collected and stored, primary teeth could be utilized to potentially treat a wide range of diseases and conditions affecting all parts of the body that a child or a close family member could develop later in life;
  19. Currently, dental stem cells are studied in some clinical trial including regeneration of pulp, periodontal and bone tissues. All studies confirmed the safety of using these cells;
  20. Although today the full potentials of primary tooth stem cells are not yet known, several researchers believe that they could be one day successfully used for the regeneration of a wide range of tissues including musculoskeletal, cardiovascular, skin, neurological and dental tissues (enamel, dentin, pulp, maxillofacial ligaments, salivary glands and more);
  21. Primary teeth stem cells are able to suppress inflammation and induce an anti-inflammatory microenvironment. Thus, they have immunosuppressive and immunomodulatory properties that are very helpful for the treatment of autoimmune diseases such as multiple sclerosis (MS);
  22. Primary teeth stem cells were stable after cryopreservation and thus can be very suitable for stem cell tissue banks;
  23. The opportunity to bank children’s dental stem cells will have the greatest future impact if collected and stored while patients are young and healthy.
  24. Children’s teeth stem cell storage offers several benefits for the patient’s future because technology and research are increasing quickly; it is a useful investment.

 Use of Stem Cells Tooth Banking

 

 

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